Tricalcium citrate – a new brittle tableting excipient for direct compression and dry granulation with enormous hardness yield
نویسندگان
چکیده
منابع مشابه
Physico-chemical comparison of famotidine tablets prepared via dry granulation and direct compression techniques.
Famotidine is generally employed for the treatment of gastric ulcer. The present study was conducted to fabricate famotidine tablets using various diluents. The binder was incorporated to the formulations in different proportions. Both the dry granulation and direct compression techniques were employed to develop the tablets. Physical evaluation of tablets i.e. tablets hardness, friability, wei...
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In the pharmaceutical industry, the three most common granulation processes for solid dosage form production are wet granulation, dry granulation (roller compaction) and direct blending. Yet, despite being well-established techniques, each has its drawbacks. Moisture-activated dry granulation (MADG) was developed in response to the difficulties experienced with wet granulation, in terms of endp...
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15 صفحه اولFlowsheet Modeling of a Continuous Direct Compression Tableting Process at Production Scale
A flowsheet model for a continuous direct compression tableting process is developed and applied to process data. The model contains powder feeding, blending and tablet compaction unit operations. The dataset was provided by Merck & Co., Inc., Kenilworth, NJ USA using a GEA ConsiGma continuous direct compression process designed for a 50 kg/h throughput using a six ingredient, potentially comme...
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ژورنال
عنوان ژورنال: Drug Development and Industrial Pharmacy
سال: 2018
ISSN: 0363-9045,1520-5762
DOI: 10.1080/03639045.2018.1483389